- Mariano Yogore was a Full Professor in the Department of Microbiology at the University of Chicago and published over 50 scientific works, he was awarded the Philippine Man of Science in 1964.
- Dr. Czarina Aya-ay Saloma-Akpedonu was granted Outstanding Young Scientist of the Philippines Award in 2007 and has published many works that have broadened the field of Sociology and Anthropology.
- Francisco Quisumbing was a chemist, he invented the world famous Quink Ink that is used in pens all over the world.
- Dr. Raymundo Santiago Punongbayan greatly advanced the understanding of volcanic eruption prediction and was the former director of the Philippine Institute of Volcanology and Seismology (PHIVOLCS)
- Baldomero Olivera is famous for the discovery of many cone snail toxins which hold great importance in the field of neuroscience.
- León María Guerrero, before a career in politics, was an influential botanist. He was respected so much so that a genus of plants, Guerreroia monocephala, and a species of orchids, Dendrobium guerreroi, are named in his honor. He was also the first licensed pharmacist in the Philippines.
- Dioscoro L. Umali's research helped improve yields of corn, rice and other economical plants, especially in upland areas.
- Fe del Mundo (born November 27, 1911) is a pioneer in the field of pediatrics. She is the founder of the first pediatric hospital in the Philippines and is believed to be the first woman admitted as a student of the Harvard Medical School
- Conrado Singian Dayrit, a former president of the Federation of Asian Scientific Academies and Societies was known as Dr. Coconut due to his advocacy of the health benefits of coconut oil.
- Paulo C. Campos was the inaugural president of the National Academy of Science and Technology and famed for his work in nuclear medicine.
